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775351-56-9

2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Catalog#: AR00377B  |   CAS#: 775351-56-9  |   MDL#: MFCD16994355  |   MF: C13H16BNO3  |   MW: 245.082

Packsize Purity Price Availability Quantity
100mg 98% $5.00 Global Stock Buy Now Add To Cart
250mg 98% $8.00 Global Stock Buy Now Add To Cart
1g 98% $25.00 Global Stock Buy Now Add To Cart
5g 98% $113.00 Global Stock Buy Now Add To Cart
25g 98% $436.00 Global Stock Buy Now Add To Cart
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Catalog Number AR00377B
Chemical Name 2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
CAS Number 775351-56-9
Molecular Formula C13H16BNO3
Molecular Weight 245.082
MDL Number MFCD16994355
SMILES N#Cc1cc(ccc1O)B1OC(C(O1)(C)C)(C)C

2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is a versatile compound commonly utilized in chemical synthesis due to its unique properties. This compound serves as a valuable building block for the synthesis of various organic molecules and pharmaceutical intermediates. Specifically, it is widely employed in Suzuki-Miyaura cross-coupling reactions, a fundamental tool in organic synthesis for forming carbon-carbon bonds. In this reaction, 2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile acts as a boronic ester, reacting with aryl halides or pseudohalides in the presence of a palladium catalyst to generate biaryl compounds. Additionally, this compound can participate in other types of transformations, such as nucleophilic aromatic substitution and Heck reactions, expanding its utility in the construction of complex organic molecules.
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