
Catalog Number	AR003660
Chemical Name	Phenyl Phosphorodichloridate
CAS Number	770-12-7
Molecular Formula	C6H5Cl2O2P
Molecular Weight	210.9825
MDL Number	MFCD00002067
SMILES	ClP(=O)(Oc1ccccc1)Cl
NSC Number	44412
UN Number	3265

Phenyl phosphorodichloridate is a versatile compound commonly used in chemical synthesis. It serves as a key intermediate in the preparation of phosphorus-containing compounds with a wide range of applications.One of the primary uses of phenyl phosphorodichloridate is as a phosphorylating agent in organic synthesis. It can effectively transfer the phosphoryl group to various nucleophilic substrates, allowing for the selective introduction of phosphorus into molecules. This property makes it particularly valuable in the synthesis of nucleoside phosphoramidites, which are essential building blocks in nucleic acid chemistry and the production of oligonucleotides.Additionally, phenyl phosphorodichloridate is employed in the acylation of alcohols and amines, enabling the formation of esters and amides, respectively. This reactivity broadens its utility in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. Furthermore, it can participate in reactions to generate phosphorus-containing heterocycles, which are prevalent in medicinal chemistry and materials science.Overall, the diverse application of phenyl phosphorodichloridate in chemical synthesis highlights its significance as a crucial reagent for the efficient construction of phosphorus-based compounds across various industries.

Phenyl Phosphorodichloridate

770-12-7

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