
Catalog Number	AR005QAG
Chemical Name	SN-38-d3
CAS Number	718612-49-8
Molecular Formula	C22H17D3N2O5
Molecular Weight	395.4231
SMILES	CC[C@@]1(O)C(=O)OCc2c1cc1c3nc4ccc(cc4c(c3Cn1c2=O)CC([2H])([2H])[2H])O

SN-38-d3 is a deuterated derivative of SN-38, a potent antitumor compound commonly used in the treatment of various types of cancer. The incorporation of deuterium into SN-38 can provide several advantages in chemical synthesis. One of the key applications of SN-38-d3 in chemical synthesis is in the field of medicinal chemistry. By using SN-38-d3 as a stable isotopic label, researchers can track and study the metabolic pathways and pharmacokinetics of SN-38 and its derivatives. This can provide valuable insights into the bioavailability, distribution, and elimination of these compounds in the body, ultimately leading to the development of more effective and safer cancer treatments.Additionally, the deuterium atoms in SN-38-d3 can act as powerful probes in structural elucidation studies. The unique properties of deuterium, such as its different bond lengths and bond strengths compared to hydrogen, can provide valuable information about the molecular structure and reactivity of SN-38 and its analogs. This can help chemists better understand the mechanisms of action of these compounds and optimize their therapeutic potential.Overall, the use of SN-38-d3 in chemical synthesis offers a versatile tool for studying the pharmacological and chemical properties of SN-38 and its derivatives, ultimately contributing to the development of innovative cancer therapies.

1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (4S)-

123948-87-8

Product Details

1,4'-bipiperidine-1'-carboxylic acid (s)-4,11-diethyl-3,4,12,14- tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester

97682-44-5

Product Details

1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-, (4S)-

190710-79-3

Product Details

(4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

19685-09-7

Product Details

Rubitecan

91421-42-0

Product Details

(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride

119413-54-6

Product Details

7-Ethylcamptothecin

78287-27-1

Product Details

Campathecin

7689-03-4

Product Details

Irinotecan Hydrochloride Trihydrate

136572-09-3

Product Details

7-Ethyl-10-hydroxycamptothecin

86639-52-3

Product Details

9-Aminocamptothecin

91421-43-1

Product Details

SN-38 Glucuronide

121080-63-5

Product Details

SN-38-d3

718612-49-8

Product Details

Camtobell hydrochloride

213819-48-8

Product Details

[1,4'-Bipiperidine]-1'-carboxylic acid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester, monohydrochloride

100286-90-6

Product Details