
Catalog Number	AR0037IL
Chemical Name	E-64
CAS Number	66701-25-5
Molecular Formula	C15H27N5O5
Molecular Weight	357.4054
MDL Number	MFCD07366493
SMILES	CC(CC(C(=O)NCCCCN=C(N)N)NC(=O)C1OC1C(=O)O)C

E-64, also known as N-(trans-epoxysuccinyl)-L-leucine 4-guanidinobutylamide, is a potent inhibitor of cysteine proteases, particularly the protease cathepsin B. In chemical synthesis, E-64 has found significant application as a tool for studying protease activity and inhibition mechanisms. By selectively targeting cysteine proteases, E-64 can be utilized to inhibit specific enzymatic pathways, allowing researchers to probe the roles of these enzymes in various biological processes.Additionally, E-64 has been utilized in the development of protease-based assays and screening methods. Its ability to block the activity of cysteine proteases makes it a valuable tool for researchers interested in identifying and characterizing novel protease inhibitors. Furthermore, E-64's stability and specificity make it a useful reagent in biochemical and cell biology studies aimed at elucidating protease functions.Moreover, the use of E-64 in chemical synthesis extends beyond enzymology to applications in drug discovery and development. By targeting specific cysteine proteases, E-64 can assist in the design and optimization of protease inhibitors for therapeutic purposes. Its well-established inhibitory properties make it a valuable starting point in the development of novel compounds for treating diseases associated with dysregulated protease activity.In summary, E-64 plays a crucial role in chemical synthesis by serving as a potent and selective inhibitor of cysteine proteases. Its applications range from fundamental research on protease function to the design of novel therapeutics, making it a versatile tool in the field of biochemistry and drug discovery.

E-64

66701-25-5

Product Details

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Product Details

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Product Details

Packsize	Purity	Price	Availability
1mg	99%	$19.00	Global Stock	Buy Now	Add To Cart
5mg	99%	$47.00	Global Stock	Buy Now	Add To Cart
10mg	99%	$79.00	Global Stock	Buy Now	Add To Cart
25mg	99%	$156.00	Global Stock	Buy Now	Add To Cart
50mg	99%	$266.00	Global Stock	Buy Now	Add To Cart
100mg	99%	$451.00	Global Stock	Buy Now	Add To Cart
250mg	99%	$767.00	Global Stock	Buy Now	Add To Cart