
Catalog Number	AR0037RM
Chemical Name	2'-Fluoro-2'-deoxyadenosine
CAS Number	64183-27-3
Molecular Formula	C10H12FN5O3
Molecular Weight	269.2324
MDL Number	MFCD09750859
SMILES	OC[C@H]1O[C@H]([C@@H]([C@@H]1O)F)n1cnc2c1ncnc2N

2'-Fluoro-2'-deoxyadenosine, commonly referred to as 2'F-A, is a key compound utilized in chemical synthesis for its unique properties and versatile applications. This modified nucleoside has found significant use in the development of nucleotide analogs and pharmaceuticals due to its ability to mimic natural adenosine while offering improved stability and bioactivity.In chemical synthesis, 2'F-A serves as a valuable building block for the creation of nucleoside analogs with enhanced properties. Its incorporation into oligonucleotides and nucleic acids can confer resistance to nuclease degradation and increase binding affinity with complementary sequences. This makes it an invaluable tool in the design of antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutics.Furthermore, the unique fluorine substitution at the 2' position of the ribose sugar in 2'F-A imparts distinct physicochemical properties that can be leveraged for specific applications. The fluorine atom not only confers increased hydrophobicity and lipophilicity but also influences the conformational preferences of the nucleoside, potentially leading to altered interactions with target molecules.Overall, the strategic incorporation of 2'-Fluoro-2'-deoxyadenosine in chemical synthesis enables researchers to fine-tune the properties of nucleotide analogs and pharmaceutical compounds, opening doors to a wide range of innovative applications in drug discovery, molecular biology, and biotechnology.

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Packsize	Purity	Price	Availability
100mg	95%	$7.00	Global Stock	Buy Now	Add To Cart
250mg	95%	$16.00	Global Stock	Buy Now	Add To Cart
1g	95%	$40.00	Global Stock	Buy Now	Add To Cart
5g	95%	$160.00	Global Stock	Buy Now	Add To Cart
10g	95%	$288.00	Global Stock	Buy Now	Add To Cart
25g	95%	$572.00	Global Stock	Buy Now	Add To Cart