
Catalog Number	AR0033J1
Chemical Name	1-Tert-Butoxy-2-Propanol
CAS Number	57018-52-7
Molecular Formula	C7H16O2
Molecular Weight	132.2007
MDL Number	MFCD00077674
SMILES	CC(COC(C)(C)C)O
UN Number	1993

1-Tert-Butoxy-2-Propanol, also known as tert-butyl 1-(hydroxymethyl)ethyl ether, is a versatile chemical compound commonly used in chemical synthesis. Its unique structure and functional groups make it a valuable reagent with a wide range of applications in organic chemistry.One prominent use of 1-Tert-Butoxy-2-Propanol in chemical synthesis is as a protecting group for alcohols. By selectively masking the hydroxyl group with the tert-butoxy moiety, this compound can prevent unwanted reactions from occurring at the alcohol functionality during various transformations. This protection strategy allows for the sequential manipulation of other functional groups in the molecule without affecting the hydroxyl group, thereby enabling efficient and selective synthesis routes.Additionally, 1-Tert-Butoxy-2-Propanol can serve as a solvent or cosolvent in organic reactions, facilitating the dissolution of reactants and improving the overall efficiency of the synthetic process. Its low volatility and high solubility in a variety of organic solvents make it a practical choice for promoting desired chemical transformations while maintaining reaction control.Furthermore, the presence of the tert-butoxy group in 1-Tert-Butoxy-2-Propanol imparts steric hindrance, which can influence the regioselectivity and stereoselectivity of certain reactions. This can be particularly advantageous in complex synthesis pathways where precise control over the spatial arrangement of functional groups is crucial for the formation of desired products.Overall, 1-Tert-Butoxy-2-Propanol's utility as a protecting group, solvent, and steric modifier underscores its significance in advancing the field of chemical synthesis, offering chemists a valuable tool for designing and executing diverse synthetic strategies with enhanced precision and efficiency.

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GHS Pictogram
Signal Word	Danger
UN#	1993
Hazard Statements	H225-H301+H311+H331-H370-H302-H336-H351-H361
Precautionary Statements	P210-P260-P280-P301+P310+P330-P308+P311-P403+P233-P261
Class	3
Packing Group	Ⅲ