(-)-Bis[(S)-1-phenylethyl]amine

(-)-Bis[(S)-1-phenylethyl]amine, also known as (S)-BIPHEN, is a chiral amine compound that finds broad application in chemical synthesis as a versatile resolving agent and chiral ligand. In organic synthesis, it is often employed as a resolving agent to separate racemic mixtures into their enantiomeric forms by forming diastereomeric salts. These resolved enantiomers can then be utilized in various asymmetric synthesis reactions to produce chiral compounds of high optical purity. Additionally, (S)-BIPHEN is frequently used as a chiral ligand in transition metal-catalyzed asymmetric reactions to facilitate enantioselective transformations. Its ability to induce stereochemical control in complex molecular structures makes it a valuable tool in the preparation of chiral pharmaceuticals, agrochemicals, and fine chemicals.