
Catalog Number	AR003LHE
Chemical Name	4-azidobenzoic acid N-hydroxysuccinimide ester
CAS Number	53053-08-0
Molecular Formula	C11H8N4O4
Molecular Weight	260.2056
MDL Number	MFCD00054963
SMILES	O=C(c1ccc(cc1)N=[N+]=[N-])ON1C(=O)CCC1=O
NSC Number	329704

4-Azidobenzoic acid N-hydroxysuccinimide ester is a versatile compound widely utilized in chemical synthesis for bioconjugation and labeling purposes. This reactive ester is commonly employed in the fields of organic chemistry and biochemistry for the efficient and specific modification of biomolecules such as proteins and peptides.One of the key applications of 4-azidobenzoic acid N-hydroxysuccinimide ester is in the area of click chemistry, where it serves as a useful tool for the functionalization of proteins and peptides through bioorthogonal reactions. By reacting with alkyne or cyclooctyne derivatives, this compound enables the selective attachment of various molecules to biomolecules under mild conditions, facilitating the creation of novel bioconjugates with tailored properties.Furthermore, the azide group in 4-azidobenzoic acid N-hydroxysuccinimide ester can participate in Staudinger ligation reactions, allowing for the site-specific labeling of proteins and peptides in biological systems. This method has proven to be valuable in studying protein-protein interactions, cellular processes, and drug discovery efforts.Overall, the utility of 4-azidobenzoic acid N-hydroxysuccinimide ester in chemical synthesis lies in its ability to introduce specific functional groups onto biomolecules, enabling researchers to probe and manipulate biological systems with precision and control.