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524046-23-9

4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-sulfonyl chloride

Catalog#: AR006V4L  |   CAS#: 524046-23-9  |   MDL#: MFCD01631923  |   MF: C13H8ClF3O2S  |   MW: 320.7146

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Catalog Number AR006V4L
Chemical Name 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-sulfonyl chloride
CAS Number 524046-23-9
Molecular Formula C13H8ClF3O2S
Molecular Weight 320.7146
MDL Number MFCD01631923
SMILES FC(c1ccc(cc1)c1ccc(cc1)S(=O)(=O)Cl)(F)F

As a professional chemist, I can provide you with a detailed description of the application of 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-sulfonyl chloride in chemical synthesis. This compound, often referred to as $name$, is a versatile reagent that finds widespread use in organic chemistry transformations. It serves as a valuable building block in the synthesis of various organic compounds due to its unique structural features and reactivity.The incorporation of the trifluoromethyl group in the biphenyl-sulfonyl chloride moiety imparts distinct properties to $name$, making it a powerful tool in the preparation of biologically active molecules, pharmaceuticals, and agrochemicals. The presence of the sulfonyl chloride functional group allows for selective derivatization of organic substrates through sulfonylation reactions, offering a pathway to introduce the biphenyl scaffold into a variety of molecular frameworks.In chemical synthesis, 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-sulfonyl chloride can act as a versatile electrophile in cross-coupling reactions, enabling the formation of carbon-carbon and carbon-heteroatom bonds. It can participate in Suzuki, Heck, and Sonogashira coupling reactions, among others, to construct complex molecular architectures efficiently. Furthermore, the trifluoromethyl group enhances the lipophilicity and metabolic stability of the resulting compounds, making them valuable candidates for drug discovery and development.Overall, the strategic incorporation of 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-sulfonyl chloride in chemical synthesis enables the access to diverse structural motifs and functionalized compounds with enhanced biological activities. Its application showcases the significant impact of innovative reagents in driving advances in synthetic chemistry and molecular design.
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