Artepillin C, a naturally occurring prenylated phenolic compound, holds significant importance in chemical synthesis due to its versatile applications. This compound, primarily isolated from Brazilian green propolis, exhibits promising antimicrobial, anti-inflammatory, and anticancer properties, making it a valuable molecule for various research purposes.In chemical synthesis, Artepillin C serves as a key building block for the creation of novel drug candidates and bioactive compounds. Its unique structure and reactivity allow for the derivation of structurally diverse analogs with potential therapeutic benefits. By utilizing Artepillin C as a starting material, chemists can engage in the development of new pharmaceuticals, agrochemicals, and functional materials through strategic modifications and derivatization approaches.Moreover, Artepillin C's multifaceted biological activities make it an attractive target for structure-activity relationship studies and drug discovery projects. Its anti-inflammatory and antioxidant properties, in particular, have sparked interest in investigating its potential as a lead compound for the development of anti-inflammatory drugs or nutraceuticals.Overall, the utilization of Artepillin C in chemical synthesis underscores its significance as a valuable tool for expanding the chemical space and exploring new avenues in drug development and molecular design.