2-Naphthalenepropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αR)-

Fmoc-3-(2-Naphthyl)-D-alanine is a versatile building block in chemical synthesis due to its usefulness in peptide chemistry and organic synthesis. This compound, commonly referred to as Fmoc-Nal-Ala-OH, is frequently employed as a key intermediate in the solid-phase synthesis of peptides with specific structural and biological properties.When incorporated into a peptide sequence, Fmoc-3-(2-Naphthyl)-D-alanine serves as a powerful tool for introducing chirality and enhancing the stability and conformation of the peptide backbone. Its unique structural features, including the 2-naphthyl group and the D-alanine amino acid, contribute to the overall stability and functionality of the synthesized peptides.Moreover, the Fmoc protection group attached to the amino terminus of Fmoc-3-(2-Naphthyl)-D-alanine enables selective deprotection under mild conditions, making it an ideal building block for stepwise peptide elongation on solid support. This controlled deprotection strategy ensures high yields and purity of the final peptide product.Overall, the strategic use of Fmoc-3-(2-Naphthyl)-D-alanine in chemical synthesis allows for the efficient assembly of complex peptide structures with tailored properties, making it an essential component in the toolbox of synthetic chemists and peptide researchers.