
Catalog Number	AR00564Y
Chemical Name	1H-Imidazole-5-carboxylic acid, 2-(trifluoromethyl)-
CAS Number	78016-98-5
Molecular Formula	C5H3F3N2O2
Molecular Weight	180.08472959999997
MDL Number	MFCD10696306
SMILES	OC(=O)c1c[nH]c(n1)C(F)(F)F

1H-Imidazole-5-carboxylic acid, 2-(trifluoromethyl), is a valuable compound widely utilized in chemical synthesis due to its unique properties and versatile reactivity. In the realm of organic chemistry, this compound serves as a key building block for the synthesis of various pharmaceuticals, agrochemicals, and organic materials. Its trifluoromethyl group imparts enhanced lipophilicity and electron-withdrawing properties, making it a valuable moiety in drug design and development.One of the primary applications of 1H-Imidazole-5-carboxylic acid, 2-(trifluoromethyl), lies in its ability to act as a versatile nucleophilic reagent in various reactions. It can participate in nucleophilic substitution, addition, and condensation reactions, leading to the formation of diverse chemical structures. In addition, the presence of the imidazole ring confers unique aromaticity and potential for hydrogen bonding interactions, further expanding its synthetic utility.Furthermore, the trifluoromethyl group attached to the imidazole core enhances the compound's stability and bioactivity, making it an attractive target for medicinal chemistry efforts. By incorporating this functional group into drug molecules, researchers can modulate the pharmacokinetic properties, metabolic stability, and binding affinity of the final compounds, thereby enhancing their efficacy and therapeutic potential.Overall, the strategic use of 1H-Imidazole-5-carboxylic acid, 2-(trifluoromethyl), in chemical synthesis enables the efficient construction of diverse molecular architectures with tailored properties, paving the way for the discovery of novel drugs, agrochemicals, and materials with enhanced performance and functionality.

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GHS Pictogram
Signal Word	Warning
UN#	N/A
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305+P351+P338
Class	N/A
Packing Group	N/A

Packsize	Purity	Price	Availability
100mg	97%	$29.00	Global Stock	Buy Now	Add To Cart
250mg	97%	$59.00	Global Stock	Buy Now	Add To Cart
500mg	97%	$98.00	Global Stock	Buy Now	Add To Cart
1g	97%	$162.00	Global Stock	Buy Now	Add To Cart

1H-​Imidazole-​5-​carboxylic acid, 2-​(trifluoromethyl)​-

1H-Imidazole-5-carboxylic acid, 2-(trifluoromethyl)-