
Catalog Number	AR003UYY
Chemical Name	Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid-NHS
CAS Number	71875-81-5
Molecular Formula	C16H18N2O6
Molecular Weight	334.3239
MDL Number	MFCD08274640
SMILES	O=C([C@@H]1CC[C@H](CC1)CN1C(=O)C=CC1=O)ON1C(=O)CCC1=O

SMCC (Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate) is a versatile crosslinker commonly used in chemical synthesis applications. It consists of two functional groups: a succinimidyl ester and a maleimide moiety. In chemical synthesis, SMCC is primarily utilized for crosslinking proteins or peptides to other molecules, such as small molecules, nucleic acids, or surfaces, through the formation of stable amide and thioether bonds. The succinimidyl ester group reacts with primary amines on proteins or peptides, while the maleimide group selectively reacts with thiol groups on cysteine residues. These reactions result in the covalent conjugation of biomolecules, allowing for the formation of protein-protein or protein-small molecule complexes.SMCC is particularly useful in the development of bioconjugates for various applications, including drug delivery, diagnostic assays, and biomaterials. By enabling the controlled and site-specific attachment of molecules, SMCC facilitates the creation of tailored conjugates with enhanced properties and functionalities. Its biocompatibility and stability make SMCC a valuable tool in the field of chemical synthesis for the precise manipulation of biomolecular interactions.

Ethanone, 1-[3,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-pyridinyl]-

1227068-67-8

$6.00/100mg, $8.00/250mg, $21.00/1g, $78.00/5g, $139.00/10g, $260.00/25g, $1,039.00/100g,

Product Details

Ethyl 4-amino-2-chloropyrimidine-5-carboxylate

71406-78-5

$6.00/100mg, $7.00/250mg, $23.00/1g, $85.00/5g, $169.00/10g,

Product Details

Potassium cyclopyropylmethyltrifluoroborate

1356481-57-6

$26.00/100mg, $36.00/250mg, $61.00/1g, $243.00/5g, $433.00/10g, $1,004.00/25g,

Product Details

Bromo-PEG2-azide

530151-56-5

$10.00/100mg, $14.00/250mg, $28.00/500mg, $41.00/1g, $129.00/5g, $256.00/10g, $572.00/25g, $996.00/50g,

Product Details

4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one

1178884-53-1

$21.00/100mg, $33.00/250mg, $52.00/1g, $139.00/5g, $208.00/10g, $381.00/25g, $693.00/50g, $1,299.00/100g,

Product Details

Perfluorophenyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate

1353012-00-6

$23.00/100mg, $43.00/250mg, $115.00/1g,

Product Details


GHS Pictogram
Signal Word	Warning
UN#	N/A
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
Class	N/A
Packing Group	N/A

Packsize	Purity	Price	Availability
100mg	98%	$7.00	Global Stock	Buy Now	Add To Cart
250mg	98%	$9.00	Global Stock	Buy Now	Add To Cart
1g	98%	$20.00	Global Stock	Buy Now	Add To Cart
5g	98%	$79.00	Global Stock	Buy Now	Add To Cart
10g	98%	$155.00	Global Stock	Buy Now	Add To Cart
25g	98%	$307.00	Global Stock	Buy Now	Add To Cart

Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid-NHS