
Catalog Number	AR00ED6M
Chemical Name	Ethanone, 2,2,2-trifluoro-1-(4-nitrophenyl)- (9CI)
CAS Number	58808-61-0
Molecular Formula	C8H4F3NO3
Molecular Weight	219.1175
MDL Number	MFCD13173414
SMILES	O=C(C(F)(F)F)c1ccc(cc1)[N+](=O)[O-]

2,2,2-Trifluoro-1-(4-nitrophenyl)ethanone is a versatile compound widely used in chemical synthesis as a key building block. Its unique chemical structure containing both a trifluoromethyl group and a nitrophenyl moiety makes it a valuable reagent in organic reactions. In synthesis, this compound acts as a powerful electrophile due to the electron-withdrawing nature of the trifluoromethyl and nitro groups, allowing for selective functionalization of various organic molecules. Additionally, the presence of the trifluoromethyl group enhances the compound's lipophilicity and can lead to improved pharmacological properties in drug design. The ability of 2,2,2-Trifluoro-1-(4-nitrophenyl)ethanone to participate in reactions such as nucleophilic additions, aromatic substitutions, and cross-coupling reactions makes it an indispensable tool in the synthesis of complex organic compounds with diverse applications in medicinal chemistry, materials science, and agrochemicals.