
Catalog Number	AR01A46Q
Chemical Name	4-(chloromethyl)-N,N-dimethylbenzene-1-sulfonamide
CAS Number	58804-19-6
Molecular Formula	C9H12ClNO2S
Molecular Weight	233.7151
MDL Number	MFCD19321817
SMILES	ClCc1ccc(cc1)S(=O)(=O)N(C)C

4-(Chloromethyl)-N,N-dimethylbenzenesulfonamide is a versatile compound used in chemical synthesis for its unique reactivity and selectivity. This compound is commonly employed as a sulfonamide protecting group in organic synthesis reactions. Its ability to form stable sulfonamide linkages allows for the protection of various functional groups during complex chemical transformations.Additionally, 4-(Chloromethyl)-N,N-dimethylbenzenesulfonamide serves as a valuable building block in the synthesis of pharmaceuticals and agrochemicals. Its chloromethyl group provides a handle for further functionalization through nucleophilic substitution reactions, enabling the introduction of diverse substituents that influence the compound's activity and properties.Furthermore, this compound can participate in cross-coupling reactions, such as Suzuki-Miyaura coupling, to form biaryl compounds with high efficiency. Its dimethylbenzenesulfonamide moiety offers a unique steric and electronic environment that can influence the regioselectivity and yield of the coupling reactions.In conclusion, the application of 4-(Chloromethyl)-N,N-dimethylbenzenesulfonamide in chemical synthesis extends beyond simple protection strategies, making it a valuable tool for the construction of complex organic molecules with tailored properties and functions.

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4-(chloromethyl)-N,N-dimethylbenzene-1-sulfonamide