
Catalog Number	AR00DC08
Chemical Name	SIS3 hydrochloride
CAS Number	521984-48-5
Molecular Formula	C28H28ClN3O3
Molecular Weight	489.9932
MDL Number	MFCD09265258
SMILES	COc1cc2CN(CCc2cc1OC)C(=O)/C=C/c1c(c2ccccc2)n(c2c1cccn2)C.Cl

SIS3, a potent and selective inhibitor of Smad3 phosphorylation, is a valuable chemical tool in the field of chemical synthesis. By specifically targeting the Smad3 protein, SIS3 allows for precise regulation of TGF-β signaling pathways, which are crucial for various cellular processes including differentiation, proliferation, and apoptosis. This inhibition of Smad3 phosphorylation can lead to significant alterations in gene expression, making SIS3 a versatile compound for investigating and manipulating various cellular responses in chemical synthesis studies. Furthermore, SIS3 has shown promising potential in the development of novel therapeutic strategies for diseases related to dysregulated TGF-β signaling, highlighting its importance in advancing research in the field of chemical biology.

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Product Details

Packsize	Purity	Price	Availability
1mg	97%	$55.00	Global Stock	Buy Now	Add To Cart
5mg	97%	$121.00	Global Stock	Buy Now	Add To Cart
25mg	97%	$219.00	Global Stock	Buy Now	Add To Cart
50mg	97%	$281.00	Global Stock	Buy Now	Add To Cart
100mg	97%	$536.00	Global Stock	Buy Now	Add To Cart

SIS3 hydrochloride