2',3-Difluoro-[1,1'-biphenyl]-4-carboxylic acid is a versatile compound commonly used in chemical synthesis as a key building block for the preparation of various pharmaceuticals, agrochemicals, and materials. With its unique structure and fluorinated substitution pattern, this compound plays a crucial role in designing and creating innovative molecules with enhanced properties.In chemical synthesis, 2',3-Difluoro-[1,1'-biphenyl]-4-carboxylic acid serves as a valuable precursor for the synthesis of biaryl compounds, which are widely employed in medicinal chemistry for drug discovery and development. The fluorine atoms on the biphenyl ring confer desirable characteristics such as increased lipophilicity, improved metabolic stability, and altered binding affinity, making it a valuable tool for designing bioactive molecules with optimized pharmacological properties.Furthermore, this compound can also be utilized as a coupling partner in cross-coupling reactions, such as Suzuki-Miyaura coupling, Negishi coupling, and Heck reaction, to construct complex molecular frameworks efficiently. By incorporating 2',3-Difluoro-[1,1'-biphenyl]-4-carboxylic acid into organic synthesis strategies, chemists can access diverse chemical space and expedite the development of new therapeutic agents, crop protection agents, and advanced materials with tailored functionalities.