
Catalog Number	AR00DB2E
Chemical Name	2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID
CAS Number	503309-10-2
Molecular Formula	C7H5BF4O3
Molecular Weight	223.9174
MDL Number	MFCD11040275
SMILES	OB(c1ccc(cc1F)OC(F)(F)F)O

As a professional chemist, I can describe the application of (2-Fluoro-4-(trifluoromethoxy)phenyl)boronic acid in chemical synthesis. (2-Fluoro-4-(trifluoromethoxy)phenyl)boronic acid, also known as TFMPBA, is a versatile organoboron compound commonly employed in organic synthesis. Its unique structure containing a boronic acid group, a fluorine atom, and a trifluoromethoxy group makes it valuable for various synthetic transformations.One of the key applications of TFMPBA is in the Suzuki-Miyaura cross-coupling reaction, a fundamental and widely used method in organic chemistry for forming carbon-carbon bonds. TFMPBA serves as a boronate source in this reaction, enabling the selective and efficient construction of biaryl compounds. The presence of the fluorine and trifluoromethoxy groups in TFMPBA can influence the electronic and steric properties of the boronic acid, leading to enhanced reactivity and selectivity in cross-coupling reactions.Furthermore, TFMPBA can also act as a halogen bond donor in crystal engineering and supramolecular chemistry. The fluorine atom in TFMPBA can participate in halogen bonding interactions with electron-rich partners, affecting molecular recognition and self-assembly processes.In summary, (2-Fluoro-4-(trifluoromethoxy)phenyl)boronic acid is a valuable reagent in chemical synthesis, particularly in Suzuki-Miyaura cross-coupling reactions and halogen bonding applications, offering unique opportunities for the construction of complex organic molecules and functional materials.

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GHS Pictogram
Signal Word	Warning
UN#	-
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305+P351+P338
Class	-
Packing Group	-

Packsize	Purity	Price	Availability
100mg	98%	$34.00	Global Stock	Buy Now	Add To Cart
250mg	98%	$56.00	Global Stock	Buy Now	Add To Cart
1g	98%	$150.00	Global Stock	Buy Now	Add To Cart
5g	98%	$524.00	Global Stock	Buy Now	Add To Cart

2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID