
Catalog Number	AR002YYU
Chemical Name	12-Crown-4
CAS Number	294-93-9
Molecular Formula	C8H16O4
Molecular Weight	176.2102
MDL Number	MFCD00005103
SMILES	O1CCOCCOCCOCC1

12-Crown-4, also known as 12-crown-4 ether, is a versatile chemical compound widely used in various chemical synthesis applications. This cyclic polyether is well-known for its ability to complex with alkali metal cations, particularly potassium ions, due to its unique crown-shaped structure with four oxygen atoms forming a ring that can encapsulate the metal ion.12-Crown-4 is commonly utilized as a phase-transfer catalyst in organic synthesis reactions, where it facilitates the transfer of ions between immiscible phases, improving reaction efficiency and yield. Its selective binding properties make it a valuable tool in coordinating metal ions during complexation reactions, helping to control the stereoselectivity and regioselectivity of the chemical processes.Furthermore, 12-Crown-4 is employed as a ligand in coordination chemistry, forming stable complexes with metal ions to enhance catalytic reactions, such as in asymmetric synthesis or cross-coupling reactions. Its ability to chelate with metal cations also finds application in extracting and separating metal ions from complex mixtures, contributing to the purification and isolation of specific compounds.In addition to its role in catalysis and coordination chemistry, 12-Crown-4 is utilized as a molecular recognition element in supramolecular chemistry, where it can selectively bind to certain guest molecules based on their size and shape, enabling the design of host-guest systems for molecular recognition and sensing applications.Overall, 12-Crown-4 plays a crucial role in chemical synthesis by serving as a versatile ligand, phase-transfer catalyst, and molecular recognition agent, offering diverse opportunities for enhancing the efficiency and selectivity of various synthetic processes.

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GHS Pictogram
Signal Word	Danger
UN#	2810
Hazard Statements	H301-H311-H330-H372
Precautionary Statements	P260-P280-P284-P301+P310-P310
Class	6.1
Packing Group	Ⅱ

Packsize	Purity	Price	Availability
250mg	98%	$18.00	Global Stock	Buy Now	Add To Cart
1g	98%	$27.00	Global Stock	Buy Now	Add To Cart
5g	98%	$117.00	Global Stock	Buy Now	Add To Cart
25g	98%	$508.00	Global Stock	Buy Now	Add To Cart